LOGIN  |  REGISTER
Astria Therapeutics

Ginkgo Bioworks Reports First Quarter 2025 Financial Results

May 06, 2025 | Last Trade: US$6.53 0.39 -5.64
  • Ginkgo provides an update on its restructuring, including progress towards its expanded $250 million cost savings target
  • Ginkgo and partners awarded $29 million contract by ARPA-H to develop distributed manufacturing of essential medicines using wheat germ cell-free expression systems

BOSTON, May 6, 2025 /PRNewswire/ -- Ginkgo Bioworks Holdings, Inc. (NYSE: DNA, "Ginkgo"), which is building the leading platform for cell programming and biosecurity, today announced its results for the first quarter ended March 31, 2025. The update, including a webcast slide presentation with additional details on the first quarter, as well as supplemental financial information will be available at investors.ginkgobioworks.com.

First Quarter 2025 Financial Results

  • First quarter 2025 Total revenue of $48 million, up from $38 million in the comparable prior year period, an increase of 27% primarily due to $7 million of non-cash revenue from the release of deferred revenue relating to the mutual termination of a customer agreement. Excluding this impact, Total revenue in the quarter was $41 million, an increase of 8% over the prior year period.
    • Excluding the $7 million non-cash deferred revenue release, first quarter 2025 Cell Engineering revenue of $31 million, up from $28 million in the comparable prior year period, an increase of 10%, primarily driven by growth with biopharma and government customers
    • First quarter 2025 Biosecurity revenue of $10 million, flat to $10 million in the comparable prior year period
  • First quarter 2025 GAAP net loss of $(91) million, compared to $(166) million in the comparable prior year period
  • First quarter 2025 Adjusted EBITDA of $(47) million, up from $(117) million in the comparable prior year period, driven by the increase in revenue as well as a decrease in operating expenses
  • Cash, cash equivalents and marketable securities balance as of March 31, 2025 of $517 million

"We're starting the year on a solid base thanks to the significant restructuring efforts of the past year," said Jason Kelly, co-founder and CEO of Ginkgo Bioworks. "Our Solutions business has become a trusted R&D service provider to the US Government and biopharma industry, meanwhile our Tools businesses have traction with existing offerings and are positioned to meet emergent opportunities in areas like AI, which are driving demand for large scale biological datasets. Through all of this, we are maintaining our commitment to achieving our cost reduction targets."

Recent Business Highlights & Strategic Positioning

  • Biotechnology remains a critical emerging technology area in the US and Ginkgo is well positioned to provide biosecurity and R&D services
    • Office of Science and Technology Policy (OSTP) Director Michael Kratsios and the National Security Commission on Emerging Biotechnology (NSCEB) report have both recently emphasized biotech as an area of national importance
    • We have 28 US Government projects across Cell Engineering and Biosecurity with ~$180M of contracted backlog and unfunded potential backlog
  • Ginkgo's Datapoints and Automation offerings are seeing new deals and opportunities emerging
    • Datapoints published GDPa1, an antibody developability dataset for 246 IgGs across 10 assays, generated using Ginkgo's high-throughput PROPHET-Ab platform
    • Automation signed a deal recently with Aura Genetics, our first diagnostics company customer
  • We made progress on our objective to reach Adjusted EBITDA breakeven by the end of 2026
    • Ginkgo's reduction in force and other cost cutting measures have achieved an annualized run-rate cost reduction of $205 million as of the first quarter of 2025, with a target to achieve $250 million in cost reduction by the end of the third quarter of 2025. Site consolidation efforts were substantially completed by the year ended 2024, with excess space available for sublease.

Full Year 2025 Guidance

  • Ginkgo previously issued 2025 guidance for Total revenue of $160-$180 million, Cell Engineering revenue of $110-$130 million; and Biosecurity revenue of at least $50 million.  Ginkgo updates its previously issued guidance solely to reflect the impact of the previously mentioned $7 million non-cash deferred revenue release in the first quarter to:
    • Total revenue of $167-$187 million in 2025;
    • Cell engineering revenue of $117-$137 million in 2025; and
    • Biosecurity revenue of at least $50 million in 2025.

Conference Call Details

Ginkgo will host a videoconference today, Tuesday, May 6, 2025, beginning at 5:30 p.m. ET. The presentation will include an overview of the first quarter of 2025, recent business updates, a discussion on Ginkgo's outlook, as well as a moderated question and answer session.

To ask a question ahead of the presentation, please submit your questions to @Ginkgo on X (hashtag #GinkgoResults) or by sending an e-mail to This email address is being protected from spambots. You need JavaScript enabled to view it..

A webcast link is available on Ginkgo's Investor Relations website and a replay will be made available following the presentation.

Ginkgo Investor Website: https://investors.ginkgobioworks.com/events/

Audio-Only Dial Ins:

+1 646 931 3860 (New York)
+1 301 715 8592 (Washington DC)
+1 305 224 1968 (Miami)
+1 312 626 6799 (Chicago)
+1 346 248 7799 (Houston)
+1 408 638 0968 (San Jose)
+1 564 217 2000 (Seattle)
+1 689 278 1000 (Orlando)

Webinar ID: 966 5095 4269

If you experience technical difficulties with any of these dial-ins or if you need international dial-in numbers, please visit our website at https://investors.ginkgobioworks.com/events/ for updated dial-in information.

About Ginkgo Bioworks

Ginkgo Bioworks is the leading horizontal platform for cell programming, providing flexible, end-to-end services that solve challenges for organizations across diverse markets, from food and agriculture to pharmaceuticals to industrial and specialty chemicals. Ginkgo Biosecurity is building and deploying the next-generation infrastructure and technologies that global leaders need to predict, detect, and respond to a wide variety of biological threats.  For more information, visit ginkgobioworks.com and ginkgobiosecurity.com, read our blog, or follow us on social media channels such as X (@Ginkgo and @Ginkgo_Biosec), Instagram (@GinkgoBioworks), Threads (@GinkgoBioworks) or LinkedIn.

Forward-Looking Statements of Ginkgo Bioworks 

This press release, the presentation, and the conference call and webcast contain certain forward-looking statements within the meaning of the federal securities laws, including statements regarding our plans, strategies, including with respect to our current expectations, operations and anticipated results of operations, both business and financial, including the timing for attaining Adjusted EBITDA breakeven, impacts of our restructuring, potential customer success, including successful application of our offerings by our customers, the regulatory landscape, and expectations with regard to revenue, including our ability to meet all milestones and achieve the maximum revenue available under certain of our customer arrangements, expenses, our full year 2025 outlook, and the market environment, all of which are subject to known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements, market trends, or industry results to differ materially from those expressed or implied by such forward-looking statements. These forward-looking statements generally are identified by the words "believe," "can," "project," "potential," "expect," "anticipate," "estimate," "intend," "strategy," "future," "opportunity," "plan," "may," "should," "will," "would," "will be," "will continue," "will likely result," and similar expressions. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this document, including but not limited to: (i) our ability to realize near-term and long-term cost savings associated with our site consolidation plans, including the ability to terminate leases or find sub-lease tenants for unused facilities, (ii) volatility in the price of Ginkgo's securities due to a variety of factors, including changes in the competitive and highly regulated industries in which Ginkgo operates and plans to operate, variations in performance across competitors, and changes in laws and regulations affecting Ginkgo's business, (iii) the ability to implement business plans, forecasts, and other expectations, and to identify and realize additional business opportunities, including with respect to our solutions and tools offerings, (iv) the risk of downturns in demand for products using synthetic biology, (v) the uncertainty regarding the demand for passive monitoring programs and biosecurity services, (vi) changes to the biosecurity industry, including due to advancements in technology, emerging competition and evolution in industry demands, standards and regulations, (vii) the outcome of any pending or potential legal proceedings against Ginkgo, (viii) our ability to realize the expected benefits from and the success of our Foundry platform programs and Codebase assets, (ix) our ability to successfully develop engineered cells, bioprocesses, data packages or other deliverables, (x) the product development, production or manufacturing success of our customers, (xi) our exposure to the volatility and liquidity risks inherent in holding equity interests in other operating companies and other non-cash consideration we may receive for our services, (xii) the potential negative impact on our business of our restructuring or the failure to realize the anticipated savings associated therewith and (xiii) the uncertainty regarding government budgetary priorities and funding allocated to government agencies. The foregoing list of factors is not exhaustive. You should carefully consider the foregoing factors and the other risks and uncertainties described in the "Risk Factors" section of Ginkgo's annual report on Form 10-K filed with the U.S. Securities and Exchange Commission (the "SEC") on February 25, 2025 and other documents filed by Ginkgo from time to time with the SEC. These filings identify and address other important risks and uncertainties that could cause actual events and results to differ materially from those contained in the forward-looking statements. Forward-looking statements speak only as of the date they are made. Readers are cautioned not to put undue reliance on forward-looking statements, and Ginkgo assumes no obligation to update or revise these forward-looking statements, whether as a result of new information, future events, or otherwise. Ginkgo does not give any assurance that it will achieve its expectations.

Use of Non-GAAP Financial Measures

Certain of the financial measures included in this release, including Adjusted EBITDA, have not been prepared in accordance with generally accepted accounting principles ("GAAP"), and constitute "non-GAAP financial measures" as defined by the SEC. Ginkgo has included these non-GAAP financial measures because it believes they provide an additional tool for investors to use in evaluating Ginkgo's financial performance and prospects. Due to the nature and/or size of the items being excluded, such items do not reflect future gains, losses, expenses or benefits and are not indicative of our future operating performance. These non-GAAP financial measures are supplemental to, and should not be considered in isolation from, or as an alternative to, financial measures determined in accordance with GAAP. In addition, these non-GAAP financial measures may differ from non-GAAP financial measures with comparable names used by other companies. See the reconciliation below for additional information regarding certain of the non-GAAP financial measures included in this release, including a description of these non-GAAP financial measures and a reconciliation of the historic measures to Ginkgo's most comparable GAAP financial measures.

Ginkgo Bioworks Contacts: 

INVESTOR CONTACT:
This email address is being protected from spambots. You need JavaScript enabled to view it. 

MEDIA CONTACT:
This email address is being protected from spambots. You need JavaScript enabled to view it. 

Ginkgo Bioworks Holdings, Inc.
Condensed Consolidated Balance Sheets
(unaudited)
(in thousands, except share data)


 

As of March 31,

 

As of December 31,

 

2025

 

2024

Assets

   

Current assets:

   

Cash and cash equivalents

$              312,420

 

$              561,572

Marketable securities

204,502

 

Accounts receivable, net

26,293

 

21,857

Accounts receivable - related parties

877

 

586

Prepaid expenses and other current assets

20,442

 

18,729

Total current assets

564,534

 

602,744

Property, plant and equipment, net

197,828

 

203,720

Operating lease right-of-use assets

383,394

 

394,435

Investments

32,173

 

48,704

Intangible assets, net

68,756

 

72,510

Other non-current assets

46,778

 

55,336

Total assets

$           1,293,463

 

$           1,377,449

Liabilities and Stockholders' Equity

   

Current liabilities:

   

Accounts payable

$                11,267

 

$                14,169

Deferred revenue

33,653

 

27,710

Accrued expenses and other current liabilities

70,747

 

65,387

Total current liabilities

115,667

 

107,266

Non-current liabilities:

   

Deferred revenue, net of current portion

80,378

 

98,783

Operating lease liabilities, non-current

434,561

 

438,766

Other non-current liabilities

15,430

 

16,576

Total liabilities

646,036

 

661,391

Commitments and contingencies

   

Stockholders' equity:

   

Preferred stock, $0.0001 par value

 

Common stock, $0.0001 par value

5

 

5

Additional paid-in capital

6,576,786

 

6,555,416

Accumulated deficit

(5,928,514)

 

(5,837,557)

Accumulated other comprehensive loss

(850)

 

(1,806)

Total stockholders' equity

647,427

 

716,058

Total liabilities and stockholders' equity

$           1,293,463

 

$           1,377,449

Ginkgo Bioworks Holdings, Inc.
Condensed Consolidated Statements of Operations and Comprehensive Loss
(unaudited)
(in thousands, except share data)


 

Three Months Ended March 31,

 

2025

 

2024

Cell Engineering revenue

$           38,230

 

$           27,889

Biosecurity revenue

10,088

 

10,055

Total revenue

48,318

 

37,944

Costs and operating expenses:

   

Cost of Biosecurity revenue (1)

7,957

 

9,202

Cost of other revenue (1)

4,090

 

Research and development (1)

70,923

 

136,457

General and administrative (1)

49,043

 

70,287

Restructuring charges

5,273

 

Total operating expenses

137,286

 

215,946

Loss from operations

(88,968)

 

(178,002)

Other income (expense):

   

Interest income, net

6,081

 

11,711

Loss on investments

(3,693)

 

(2,544)

Change in fair value of warrant liabilities

 

940

Other income (expense), net

(4,289)

 

2,015

Total other income (expense)

(1,901)

 

12,122

Loss before income taxes

(90,869)

 

(165,880)

Income tax expense

88

 

31

Net loss

$          (90,957)

 

$       (165,911)

Net loss per share:

   

Basic

$              (1.68)

 

$              (3.31)

Diluted

$              (1.68)

 

$              (3.32)

Weighted average common shares outstanding:

   

Basic

54,241,619

 

50,111,460

Diluted

54,241,619

 

50,133,366

Comprehensive loss:

   

Net loss

$          (90,957)

 

$       (165,911)

Other comprehensive (loss) income:

   

Foreign currency translation adjustment

849

 

(3,035)

Unrealized gains on available-for-sale securities

107

 

Total other comprehensive (loss) income

956

 

(3,035)

Comprehensive loss

$          (90,001)

 

$       (168,946)

 

(1)     Total stock-based compensation expense, inclusive of employer payroll taxes, was allocated as follows (in thousands):

 
 

Three Months Ended March 31,

 

2025

 

2024

Research and development

$              9,184

 

$           24,120

General and administrative

9,912

 

18,277

Cost of Biosecurity revenue

735

 

Cost of other revenue

969

 

Total

$           20,800

 

$           42,397

Ginkgo Bioworks Holdings, Inc.
Condensed Consolidated Statements of Cash Flows
(unaudited)
(in thousands)


 

Three Months Ended March 31,

 

2025

 

2024

Cash flows from operating activities:

   

Net loss

$         (90,957)

 

$       (165,911)

Adjustments to reconcile net loss to net cash used in operating activities:

Depreciation and amortization

15,366

 

12,869

Stock-based compensation

20,431

 

40,782

Loss on investments

3,693

 

2,544

Change in fair value of notes receivable

5,285

 

Change in fair value of warrant liabilities

 

(940)

Change in fair value of contingent consideration

(1,302)

 

(926)

Non-cash lease expense

7,379

 

5,637

Non-cash in-process research and development

 

16,816

Other non-cash activity

149

 

(442)

Changes in operating assets and liabilities:

   

Accounts receivable

(4,693)

 

(6,770)

Prepaid expenses and other current assets

462

 

1,154

Operating lease right-of-use assets

3,675

 

Other non-current assets

(167)

 

(707)

Accounts payable, accrued expenses and other current liabilities

6,419

 

10,871

Deferred revenue, current and non-current

(12,471)

 

(2,912)

Operating lease liabilities, current and non-current

(4,790)

 

(4,097)

Other non-current liabilities

 

2,773

Net cash used in operating activities

(51,521)

 

(89,259)

Cash flows from investing activities:

   

Purchases of marketable debt securities

(191,182)

 

Purchases of property and equipment

(7,622)

 

(6,710)

Business acquisition

 

(5,400)

Other

120

 

Net cash used in investing activities

(198,684)

 

(12,110)

Cash flows from financing activities:

   

Proceeds from exercise of stock options

 

70

Principal payments on finance leases

(207)

 

(294)

Contingent consideration payment

 

(621)

Net cash used in financing activities

(207)

 

(845)

Effect of foreign exchange rates on cash and cash equivalents

74

 

(157)

Net decrease in cash, cash equivalents and restricted cash

(250,338)

 

(102,371)

    

Cash and cash equivalents, beginning of period

561,572

 

944,073

Restricted cash, beginning of period

44,171

 

45,511

Cash, cash equivalents and restricted cash, beginning of period

605,743

 

989,584

    

Cash and cash equivalents, end of period

312,420

 

840,440

Restricted cash, end of period

42,985

 

46,773

Cash, cash equivalents and restricted cash, end of period

$          355,405

 

$          887,213

Ginkgo Bioworks Holdings, Inc.

Segment Information

(in thousands, unaudited)

  
 

Three Months Ended March 31,

 

2025

 

2024

Cell Engineering

   

Revenue

$                38,230

 

$                27,889

Costs and operating expenses:

   

   Cost of other revenue

3,121

 

   Research and development

48,670

 

81,898

   General and administrative

18,027

 

38,244

Cell Engineering operating loss

(31,588)

 

(92,253)

Biosecurity

   

Revenue

10,088

 

10,055

Costs and operating expenses:

   

   Cost of Biosecurity revenue

7,223

 

9,202

   Research and development

 

120

   General and administrative

8,050

 

11,951

Biosecurity operating loss

(5,185)

 

(11,218)

Total segment operating loss

(36,773)

 

(103,471)

Reconciling items to reconcile total segment operating loss to loss before income taxes:

Stock-based compensation (1)

20,800

 

42,397

Depreciation and amortization

15,366

 

12,869

Restructuring charges (2)

5,273

 

Carrying cost of excess space (net of sublease income) (3)

11,674

 

Merger and acquisition related expense (income) (4)

(918)

 

2,394

Acquired in-process research and development

 

16,871

Other (income) expense, net (5)

1,901

 

(12,122)

Loss before income taxes

$              (90,869)

 

$            (165,880)

  

(1)

Includes $0.4 million and $1.6 million in employer payroll taxes for the three months ended March 31, 2025 and 2024, respectively.

  

(2)

Restructuring charges primarily consist of employee termination costs from the reduction in force commenced in June 2024.

  

(3)

The carrying cost of excess space includes base rent, common area maintenance charges, and real estate taxes associated with facilities the Company is not occupying, net of any sublease income from these spaces.

  

(4)

Represents transaction and integration costs directly related to mergers and acquisitions, including: (i) legal, consulting, and accounting fees associated with acquisitions; (ii) post-acquisition employee retention bonuses; (iii) (gain)/loss from changes in the fair value of contingent consideration liabilities resulting from acquisitions; and (iv) costs associated with the Zymergen Bankruptcy, as well as securities litigation costs.

  

(5)

Includes interest income, interest expense, loss on investments, changes in fair value of certain assets and liabilities, and other gains and losses.

Ginkgo Bioworks Holdings, Inc.

Selected Non-GAAP Financial Measures

(in thousands, unaudited)

 
 

Three Months Ended March 31,

(in thousands)

2025

 

2024

Net loss (1)

$          (90,957)

 

$       (165,911)

Interest income, net

(6,081)

 

(11,711)

Income tax expense

88

 

31

Depreciation and amortization

15,366

 

12,869

EBITDA

(81,584)

 

(164,722)

Stock-based compensation (2)

20,800

 

42,397

Restructuring charges (3)

5,273

 

Loss on investments

3,693

 

2,544

Change in fair value of warrant liabilities

 

(940)

Merger and acquisition related expense (income) (4)

(918)

 

2,394

Change in fair value of convertible notes

5,285

 

1,326

Adjusted EBITDA

$          (47,451)

 

$       (117,001)

  

(1)

All periods include non-cash revenue when earned, including $7.5 million in the three months ended March 31, 2025 recognized pursuant to the termination of revenue contracts with BiomEdit.

  

(2)

Includes $0.4 million and $1.6 million in employer payroll taxes for the three months ended March 31, 2025 and 2024, respectively.

  

(3)

Restructuring charges primarily consist of employee termination costs from the reduction in force commenced in June 2024.

  

(4)

Represents transaction and integration costs directly related to mergers and acquisitions, including: (i) legal, consulting, and accounting fees associated with acquisitions; (ii) post-acquisition employee retention bonuses; (iii) (gain)/loss from changes in the fair value of contingent consideration liabilities resulting from acquisitions; and (iv) costs associated with the Zymergen Bankruptcy, as well as securities litigation costs. Not included in this adjustment are acquired in-process research and development expenses, which totaled zero and $16.9 million for the three months ended March 31, 2025 and 2024, respectively.

Recursion

Stock Quote

Featured Stock

C4 Therapeutics

C4 Therapeutics is pioneering a new class of small-molecule drugs that selectively destroy disease-causing proteins via degradation using the innate machinery of the cell. This targeted protein degradation approach offers advantages over traditional drugs, including the potential to treat a wider range of diseases...

CLICK TO LEARN MORE

Featured Stock

Amneal Pharmaceuticals

Amneal Pharmaceuticals is a fully-integrated essential medicines company. We make healthy possible through the development, manufacturing, and distribution of generic and specialty pharmaceuticals. The Company has a diverse portfolio of over 250 products in its Generics segment and is expanding across...

CLICK TO LEARN MORE

End of content

No more pages to load

Next page