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Tiziana Life Sciences to Dose First Patient in Phase 2 Alzheimer’s Trial

December 12
Last Trade: 1.78 0.06 3.49

First Patient Expected to be Dosed Next Week with Intranasal Foralumab PET Scan Shows Presence of Untreated Neuroinflammation in Alzheimer’s Patient on Leqembi® (Lecanemab) Anti-Amyloid Therapy BOSTON, Dec. 12, 2025 (GLOBE NEWSWIRE) -- Tiziana Life Sciences, Ltd. (Nasdaq:...Read more


Updated data for Eli Lilly's Inluriyo™ (imlunestrant) reinforce efficacy results as monotherapy and in combination with Verzenio®...

December 12
Last Trade: 1,027.50 18.12 1.80

As monotherapy, imlunestrant demonstrated an 11.4-month numeric improvement in median OS versus endocrine therapy in patients with ESR1-mutated disease In all patients, the imlunestrant plus abemaciclib combination achieved a median PFS of 10.9 months, demonstrated a favorable OS...Read more


Actinium Pharmaceuticals Presents New Preclinical Data Demonstrating Potent Anti-Tumor Activity of ATNM-400 Across Multiple Breast...

December 12
Last Trade: 1.51 0.06 4.14

ATNM-400's target antigen is overexpressed in breast cancer and its expression is further increased in breast cancer cells resistant to standard of care endocrine therapy, tamoxifen and the HER2 therapy trastuzumab The Actinium-225 alpha-emitter payload of ATNM-400 induced...Read more


Milestone Pharmaceuticals Receives FDA Approval of CARDAMYST™ (etripamil) as First and Only Self-Administered Nasal...

December 12
Last Trade: 2.40 -0.55 -18.64

First FDA approved treatment in 30+ years for more than 2 million Americans with PSVT  Novel nasal spray designed to rapidly resolve episodes of PSVT and restore sinus rhythm FDA approval in PSVT enables development of AFib-RVR under sNDA pathway Milestone well-capitalized to launch and...Read more


Innoviva: U.S. FDA Approves NUZOLVENCE® (zoliflodacin), a First-in-Class, Single-dose, Oral Antibiotic for the Treatment...

December 12
Last Trade: 20.63 0.01 0.05

FDA approval was based on results from the largest Phase 3 clinical trial ever conducted for a new treatment against Neisseria gonorrhoeae infection in regions with a high prevalence of gonorrhea across five countries. NUZOLVENCE is one of the first new treatments approved by the FDA for...Read more


Emergent BioSolutions Receives U.S. FDA Approval for Drug Product Manufacturing of raxibacumab at its Winnipeg, Canada Site...

December 12
Last Trade: 11.41 -0.31 -2.65

GAITHERSBURG, Md., Dec. 12, 2025 (GLOBE NEWSWIRE) -- Emergent BioSolutions (NYSE: EBS) today announced that the U.S. Food and Drug Administration (FDA) has approved its supplemental Biologics License Application (sBLA) for its Winnipeg, Canada facility to be added as the drug product manufacturing...Read more


Featured Stock

Astria Therapeutics

Astria Therapeutics is a biopharmaceutical company, and our mission is to bring life-changing therapies to patients and families affected by rare and niche allergic and immunological diseases. Our lead program, STAR-0215, is a monoclonal antibody inhibitor of plasma kallikrein in clinical development...

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Biggest Gainers

 
CompanyChangeLast Trade
Eli Lilly 18.12 1.80 $1,027.50
Ascendis Pharma 10.26 4.88 $220.42
Ligand Pharmaceuticals 6.42 3.51 $189.55
Movano Health 6.31 202.89 $9.42
Vertex Pharmaceuticals 6.11 1.37 $452.04
United Therapeutics 5.48 1.12 $493.99
Bolt Biotherapeutics 4.88 871.43 $5.44
UnitedHealth 4.57 1.36 $341.30
Celcuity 4.48 4.45 $105.25
Vera Therapeutics 3.78 8.21 $49.80
Nektar Therapeutics 3.58 7.00 $54.70
Lantheus 3.52 5.58 $66.62
Protagonist Therapeutics 3.10 3.36 $95.35
Galecto 2.99 10.31 $32.00
Jazz Pharmaceuticals 2.61 1.58 $167.50
Cytokinetics 2.58 4.25 $63.35
Soleno Therapeutics 2.51 5.07 $52.00
Cigna 2.44 0.90 $274.70

Highest Volume

 
CompanyVolumeLast Trade
WORK Medical Technology 959,635,251 $0.12
Tenaya Therapeutics 135,813,555 $0.84
Applied Therapeutics 133,947,267 $0.12
Rezolute 123,320,455 $1.67
HeartBeam 118,804,773 $2.27
Milestone Pharmaceuticals 74,386,344 $2.40
Pfizer 49,784,736 $25.85
BeyondSpring 49,625,361 $2.12
Incannex Healthcare 43,592,570 $0.43
ImmunityBio 43,061,812 $2.37
Iovance Biotherapeutics 35,112,791 $2.20
Intensity Therapeutics 21,161,482 $0.46
Bristol-Myers Squibb 18,744,678 $52.41
Moderna 16,057,766 $29.46
Geron 15,505,706 $1.36
Ocugen 15,445,384 $1.36
Electromedical Technologies 14,671,824 $0.00
Wave Life Sciences 14,647,110 $16.56
Recursion 14,614,448 $4.33
  • Upcoming FDA Catalysts

    • Innoviva (NASDAQ: INVA) PDUFA Date

      December 15, 2025
    • Aldeyra Therapeutics (NASDAQ: ALDX) PDUFA Date

      December 16, 2025
    • Cytokinetics (NASDAQ: CYTK) PDUFA Date

      December 26, 2025
    • Outlook Therapeutics (NASDAQ: OTLK) PDUFA Date

      December 31, 2025
    • Denali Therapeutics (NASDAQ: DNLI) PDUFA Date

      January 5, 2026
    • Atara Biotherapeutics (NASDAQ: ATRA) PDUFA Date

      January 10, 2026

Featured Stock

ClearPoint Neuro

ClearPoint Neuro is a global therapy-enabling platform company providing stereotactic navigation and delivery to the brain. Applications of our ClearPoint Neuro Navigation System include electrode lead placement, placement of catheters, and biopsy. The platform has FDA clearance and is...

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Featured Stock

Compass Therapeutics

Compass Therapeutics is a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases. The company's scientific focus is on the relationship between angiogenesis, the immune system, and tumor growth...

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Featured Stock

Amneal Pharmaceuticals

Amneal Pharmaceuticals is a fully-integrated essential medicines company. We make healthy possible through the development, manufacturing, and distribution of generic and specialty pharmaceuticals. The Company has a diverse portfolio of over 250 products in its Generics segment and is expanding across...

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Featured Stock

Terns Pharmaceuticals

Terns Pharmaceuticals is a clinical-stage biopharmaceutical company developing a portfolio of small-molecule product candidates to address serious diseases, including oncology and obesity. Terns’ pipeline contains three clinical stage development programs including a small-molecule GLP-1 receptor...

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