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Lantern Pharma Reports Additional Positive LP-184 Phase 1a Results Showing Durable Disease Control in Heavily Pre-Treated Advanced...

December 3
Last Trade: 3.49 0.02 0.46

Biomarker-activated cancer drug-candidate LP-184 demonstrates encouraging efficacy signals in DNA damage repair deficient tumors with an acceptable safety and tolerability profile – meeting all primary endpoints. LP-184 demonstrated clinical benefit in multiple highly aggressive...Read more


Protara Therapeutics Announces Updated Interim Data from Phase 2 ADVANCED-2 Trial of TARA-002 in BCG-Naïve NMIBC Patients

December 3
Last Trade: 6.69 0.46 7.40

TARA-002 demonstrates 72% complete response rate at any time in BCG-Naïve patients TARA-002 demonstrates a 69% complete response rate at the 6-month landmark and a 50% complete response rate at the 12-month landmark in BCG-Naïve patients Favorable safety and tolerability profile...Read more


Crinetics Pharmaceuticals Announces First Patient Dosed in Phase 1/2 Trial Evaluating CRN09682 for the Treatment of Neuroendocrine...

December 3
Last Trade: 47.16 2.15 4.78

Initiation of trial marks milestone for Crinetics’ novel nonpeptide drug conjugate platform SAN DIEGO, Dec. 03, 2025 (GLOBE NEWSWIRE) -- Crinetics Pharmaceuticals, Inc. (Nasdaq: CRNX) today announced the first patient has been dosed in the Phase 1/2 study evaluating CRN09682 in...Read more


U.S. FDA approves expanded indication for Eli Lilly's Jaypirca (pirtobrutinib), the first and only non-covalent...

December 3
Last Trade: 1,034.15 -11.97 -1.14

Approval is based on results from the BRUIN CLL-321 trial, the only randomized Phase 3 study in CLL/SLL in which all patients were previously treated with a covalent BTK inhibitor This expanded indication represents a substantial increase in the number of CLL/SLL patients who may benefit from...Read more


PolyPid Announces Positive FDA Pre-NDA Meeting Minutes for D-PLEX₁₀₀ Supporting NDA Submission

December 3
Last Trade: 3.91 0.13 3.44

NDA to be Submitted on a Rolling Basis, Beginning Early 2026 PETACH TIKVA, Israel, Dec. 03, 2025 (GLOBE NEWSWIRE) -- PolyPid Ltd. (Nasdaq: PYPD) (“PolyPid” or the “Company”), a late-stage biopharma company aiming to improve surgical outcomes, today announced that it has received a formal...Read more


Incannex Healthcare Granted FDA Fast Track Designation for IHL-42X in Obstructive Sleep Apnea (OSA)

December 3
Last Trade: 0.47 0.07 18.51

MELBOURNE, Australia and NEW YORK, Dec. 03, 2025 (GLOBE NEWSWIRE) -- Incannex Healthcare Inc. (Nasdaq: IXHL), a clinical-stage biopharmaceutical company developing innovative combination therapies, announces that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for...Read more


Featured Stock

Recursion

Recursion is a clinical stage TechBio company leading the space by decoding biology to industrialize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously expands one of the world’s largest proprietary biological and chemical datasets...

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Biggest Gainers

 
CompanyChangeLast Trade
Vertex Pharmaceuticals 27.61 6.37 $460.76
Capricor Therapeutics 21.47 337.58 $27.83
UnitedHealth 15.03 4.63 $339.57
Humana 14.40 5.95 $256.37
West Pharmaceutical 10.59 3.88 $283.62
Charles River Laboratories 10.56 6.04 $185.32
Arrowhead Pharmaceuticals 7.73 13.34 $65.68
Spruce Biosciences 7.69 8.62 $96.89
Amgen 7.64 2.26 $346.00
United Therapeutics 7.49 1.58 $481.63
Sutro Biopharma 7.25 992.77 $7.98
Praxis Precision Medicines 7.24 4.04 $186.36
ICON 6.71 3.66 $189.85
Movano Health 6.44 207.07 $9.55
AbbVie 6.07 2.71 $230.44
Apogee Therapeutics 5.56 8.04 $74.69
Madrigal Pharmaceuticals 5.13 0.90 $578.29
Bolt Biotherapeutics 4.72 844.54 $5.28

Highest Volume

 
CompanyVolumeLast Trade
Virax Biolabs 592,666,623 $0.64
Incannex Healthcare 532,010,663 $0.47
Clearmind Medicine 85,918,885 $0.11
Immuron 73,608,070 $1.56
Capricor Therapeutics 68,193,743 $27.83
Artelo Biosciences 58,025,175 $1.71
Sangamo Therapeutics 42,581,338 $0.48
Pfizer 37,125,452 $25.72
29,818,875 $4.61
Acadia Healthcare 29,782,851 $14.64
Black Diamond Therapeutics 26,385,818 $2.58
ImmunityBio 21,194,541 $2.19
Fractyl Health 21,111,746 $1.88
Bristol-Myers Squibb 19,578,590 $51.17
Mereo BioPharma 19,260,337 $1.94
Ocugen 17,641,954 $1.20
ProPhase Labs 17,478,671 $0.14
Geron 16,716,185 $1.28
Palisade Bio 15,296,285 $1.67
  • Upcoming FDA Catalysts

    • Bristol-Myers Squibb (NYSE: BMY) PDUFA Date

      December 5, 2025
    • Milestone Pharmaceuticals (NASDAQ: MIST) PDUFA Date

      December 13, 2025
    • Innoviva (NASDAQ: INVA) PDUFA Date

      December 15, 2025
    • Aldeyra Therapeutics (NASDAQ: ALDX) PDUFA Date

      December 16, 2025
    • Cytokinetics (NASDAQ: CYTK) PDUFA Date

      December 26, 2025
    • Outlook Therapeutics (NASDAQ: OTLK) PDUFA Date

      December 31, 2025

Featured Stock

Compass Therapeutics

Compass Therapeutics is a clinical-stage, oncology-focused biopharmaceutical company developing proprietary antibody-based therapeutics to treat multiple human diseases. The company's scientific focus is on the relationship between angiogenesis, the immune system, and tumor growth...

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Featured Stock

Amneal Pharmaceuticals

Amneal Pharmaceuticals is a fully-integrated essential medicines company. We make healthy possible through the development, manufacturing, and distribution of generic and specialty pharmaceuticals. The Company has a diverse portfolio of over 250 products in its Generics segment and is expanding across...

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Featured Stock

Chimerix

Chimerix is on a mission to develop medicines that meaningfully improve and extend the lives of patients facing deadly diseases. The company is devoted to filling gaps in the treatment paradigm. Chimerix’s most advanced clinical-stage program is in development for H3 K27M-mutant glioma....

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Featured Stock

ClearPoint Neuro

ClearPoint Neuro is a global therapy-enabling platform company providing stereotactic navigation and delivery to the brain. Applications of our ClearPoint Neuro Navigation System include electrode lead placement, placement of catheters, and biopsy. The platform has FDA clearance and is...

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