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Molecular Partners presents new preclinical data on Radio-DARPin and Switch-DARPin programs at AACR 2025

April 25
Last Trade: 4.50 0.42 10.29

Positive IND-enabling data on MP0712 targeting DLL3, the most advanced Radio-DARPin program in co-development with Orano Med, entering clinical development in 2025 First preclinical data of novel targeted Radio-DARPin against mesothelin (MSLN), in co-development with Orano...Read more


Pyxis Oncology Presents Promising Preclinical Results Providing Proof of Mechanism of Micvotabart Pelidotin, the First-in-Concept...

April 25
Last Trade: 1.06 -0.03 -2.75

Gene signatures associated with increased efficacy of micvotabart pelidotin (MICVO) due to greater linker cleavage were identified based on differential gene expression analysis of PDX responders/non-responders Mouse analog of MICVO in a syngeneic model indicated strong activity...Read more


ALX Oncology Announces Encouraging Final Results from Phase 1 Trial Evaluating Evorpacept in Combination with Standard-of-Care...

April 25
Last Trade: 0.54 -0.06 -9.82

Data to be presented at AACR 2025 Annual Meeting suggest the combination of ALX Oncology’s investigational CD47-blocker, evorpacept, plus rituximab and lenalidomide (R2) was well-tolerated and demonstrated promising anti-tumor activity Combination generated complete responses...Read more


Medtronic receives FDA approval for smallest-diameter, lumenless defibrillation lead, the OmniaSecure™ lead and...

April 25
Last Trade: 84.16 -0.14 -0.17

Adding to the Medtronic portfolio of catheter-based lead solutions, the novel OmniaSecure defibrillation lead allows for precise delivery and placement in the right ventricle Heart Rhythm 2025: Late-breaking clinical study results evaluating the OmniaSecure lead for investigational use in the...Read more


VYNE Therapeutics Provides Update on VYN202 Program

April 25
Last Trade: 1.45 -0.43 -22.87

BRIDGEWATER, N.J., April 25, 2025 (GLOBE NEWSWIRE) -- VYNE Therapeutics Inc. (Nasdaq: VYNE) (“VYNE” or the “Company”) today announced that the U.S. Food and Drug Administration (FDA) verbally informed the Company that it placed a clinical hold on the Company’s Phase 1b study evaluating VYN202 for...Read more


AbbVie Submits Biologics License Application to U.S. FDA for TrenibotulinumtoxinE (TrenibotE) for the Treatment of...

April 24
Last Trade: 186.47 -17.61 -8.63

TrenibotE is a first-in-class botulinum neurotoxin serotype E characterized by a rapid onset of action as early as 8 hours after administration (earliest assessment time) and shorter duration of effect of 2-3 weeks.  If approved, TrenibotE will be the first neurotoxin of its kind...Read more


Featured Stock

Immix Biopharma

Immix Biopharma is a clinical-stage biopharmaceutical company pioneering a novel class of CAR-T cell therapies and Tissue-Specific Therapeutics targeting oncology and immuno-dysregulated diseases with >75 patients treated to-date. The company's lead cell therapy asset is NXC-201 in multiple myeloma...

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Biggest Gainers

 
CompanyChangeLast Trade
Eli Lilly 24.85 2.89 $884.58
argenx 14.25 2.37 $614.76
Encompass Health 11.96 11.79 $113.37
Chemed 8.96 1.64 $555.74
Alnylam Pharmaceuticals 8.95 3.69 $251.56
Madrigal Pharmaceuticals 6.86 2.14 $326.79
Aclarion 6.76 901.33 $7.51
McKesson 6.57 0.95 $695.00
Intuitive 6.46 1.27 $514.59
Stryker 4.01 1.11 $365.06
West Pharmaceutical 3.96 1.88 $214.55
Ascendis Pharma 3.70 2.31 $164.15
Merck 2.90 3.63 $82.74
Regeneron Pharmaceuticals 2.88 0.48 $602.64
OpGen 2.87 151.05 $4.77
Jaguar Health 2.84 35.24 $10.90
Addus HomeCare 2.54 2.59 $100.58
Semler Scientific 2.40 6.97 $36.84

Highest Volume

 
CompanyVolumeLast Trade
Sharps Technology 74,222,588 $0.02
Azitra 42,561,658 $0.31
China SXT Pharmaceuticals 37,822,363 $2.37
Pfizer 34,342,718 $22.92
Merck 27,387,547 $82.74
Summit Therapeutics 24,375,957 $23.17
Acrivon Therapeutics 15,994,031 $1.64
Bristol-Myers Squibb 15,963,969 $47.90
Gilead Sciences 14,007,265 $103.17
Insmed 13,585,902 $69.69
Novavax 13,014,900 $6.67
Recursion 12,600,429 $5.69
Iovance Biotherapeutics 12,413,776 $3.51
AbbVie 10,352,092 $186.47
PacBio 9,662,403 $1.11
Viatris 9,097,427 $8.13
UnitedHealth 9,010,635 $418.98
Tempus AI 8,942,642 $52.87
Centene 8,408,467 $57.44
  • Upcoming FDA Catalysts

    • Abeona Therapeutics (NASDAQ: ABEO) PDUFA Date

      April 29, 2025
    • Arcutis Biotherapeutics (NASDAQ: ARQT) PDUFA Date

      May 22, 2025
    • UroGen Pharma (NASDAQ: URGN) PDUFA Date

      June 13, 2025
    • KalVista Pharmaceuticals (NASDAQ: KALV) PDUFA Date

      June 17, 2025
    • Merck (NYSE: MRK) PDUFA Date

      June 23, 2025
    • Regeneron Pharmaceuticals (NASDAQ: REGN) PDUFA Date

      July 10, 2025

Featured Stock

Recursion

Recursion is a clinical stage TechBio company leading the space by decoding biology to industrialize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously expands one of the world’s largest proprietary biological and chemical datasets...

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Featured Stock

C4 Therapeutics

C4 Therapeutics is pioneering a new class of small-molecule drugs that selectively destroy disease-causing proteins via degradation using the innate machinery of the cell. This targeted protein degradation approach offers advantages over traditional drugs, including the potential to treat a wider range of diseases...

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Featured Stock

Astria Therapeutics

Astria Therapeutics is a biopharmaceutical company, and our mission is to bring life-changing therapies to patients and families affected by rare and niche allergic and immunological diseases. Our lead program, STAR-0215, is a monoclonal antibody inhibitor of plasma kallikrein in clinical development...

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Featured Stock

Amneal Pharmaceuticals

Amneal Pharmaceuticals is a fully-integrated essential medicines company. We make healthy possible through the development, manufacturing, and distribution of generic and specialty pharmaceuticals. The Company has a diverse portfolio of over 250 products in its Generics segment and is expanding across...

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