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Medtronic initiates global pivotal study of cardiac pacing in a new patient population

September 15
Last Trade: 93.48 -0.56 -0.60

Study to evaluate whether a new approach to pacing the heart can improve the lives of patients with heart failure with preserved ejection fraction (HFpEF) who have limited treatment options today GALWAY, Ireland, Sept. 15, 2025 /PRNewswire/ -- Medtronic plc (NYSE: MDT), a...Read more


Spyre Therapeutics Doses First Patient in Pioneering Phase 2 SKYWAY Basket Trial of SPY072, the First Anti-TL1A Antibody Studied...

September 15
Last Trade: 14.89 -0.76 -4.86

SPY072 is a potential first- and best-in-class anti-TL1A antibody for rheumatic diseases targeting quarterly or twice-yearly subcutaneous dosing SKYWAY study is evaluating SPY072 in patients with moderate-to-severely active rheumatoid arthritis (RA), psoriatic arthritis (PsA),...Read more


aTyr Pharma Announces Topline Results from Phase 3 EFZO-FIT™ Study of Efzofitimod in Pulmonary Sarcoidosis

September 15
Last Trade: 1.03 -5.00 -82.92

Study did not meet primary endpoint in change from baseline in mean daily oral corticosteroid (OCS) dose at week 48, although clinical benefit for efzofitimod observed across multiple study parameters. 52.6% of patients treated with 5.0 mg/kg efzofitimod achieved complete steroid...Read more


Krystal Biotech Announces FDA Approval of Updated VYJUVEK® Label

September 15
Last Trade: 155.98 12.30 8.56

Revised label allows treatment of DEB patients from birth VYJUVEK can now be applied by patients and caregivers PITTSBURGH, Sept. 15, 2025 (GLOBE NEWSWIRE) -- Krystal Biotech, Inc. (the “Company”) (NASDAQ: KRYS) announced today that the United States Food and Drug Administration (FDA)...Read more


Merck: Raludotatug Deruxtecan Granted Breakthrough Therapy Designation by U.S. FDA for Patients with CDH6 Expressing...

September 15
Last Trade: 81.32 -1.49 -1.80

First Breakthrough Therapy Designation for Daiichi Sankyo and Merck’s raludotatug deruxtecan based on phase 1 trial and REJOICE-Ovarian01 phase 2/3 trial Second Breakthrough Therapy Designation since the start of the Daiichi Sankyo and Merck collaboration Fifteenth Breakthrough Therapy...Read more


Tempus AI Receives U.S. FDA Special 510(k) Clearance for Updated Tempus Pixel Device

September 11
Last Trade: 84.88 -1.50 -1.74

CHICAGO / Sep 11, 2025 / Business Wire / Tempus AI, Inc. (NASDAQ: TEM), a technology company leading the adoption of AI to advance precision medicine, today announced it has received 510(k) clearance from the U.S. Food and Drug Administration (FDA) for its updated Tempus Pixel, an AI-powered cardiac...Read more


Featured Stock

Chimerix

Chimerix is on a mission to develop medicines that meaningfully improve and extend the lives of patients facing deadly diseases. The company is devoted to filling gaps in the treatment paradigm. Chimerix’s most advanced clinical-stage program is in development for H3 K27M-mutant glioma....

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Biggest Gainers

 
CompanyChangeLast Trade
Regeneron Pharmaceuticals 12.40 2.21 $572.40
Krystal Biotech 12.30 8.56 $155.98
Palatin Technologies 8.23 4,331.58 $8.42
Biodesix 6.97 1,858.96 $7.35
IDEXX Laboratories 6.27 0.98 $647.41
Illumina 4.99 5.25 $100.11
Monopar Therapeutics 4.97 10.10 $54.19
Mettler-Toledo 4.88 0.39 $1,264.42
Bolt Biotherapeutics 4.76 850.00 $5.32
NanoVibronix 4.23 65.18 $10.72
Medpace 4.23 0.86 $495.01
West Pharmaceutical 3.88 1.53 $257.38
Clearside Biomedical 3.69 1,155.09 $4.01
Waters 3.15 1.07 $298.44
Harrow 2.96 7.51 $42.38
SIGA Technologies 2.91 47.09 $9.09
Natera 2.81 1.67 $171.32
Agilent Technologies 2.45 1.99 $125.69

Highest Volume

 
CompanyVolumeLast Trade
bioAffinity Technologies 211,182,985 $0.36
aTyr Pharma 161,902,143 $1.03
Check-Cap 119,887,876 $2.38
Adaptimmune Therapeutics 75,274,994 $0.07
NanoVibronix 61,847,983 $10.72
Pfizer 42,321,075 $23.96
Monte Rosa Therapeutics 37,095,196 $7.05
ImmunityBio 24,816,822 $2.66
Incannex Healthcare 22,018,216 $0.53
AVITA Medical 21,647,712 $6.65
Recursion 20,554,853 $4.74
Intensity Therapeutics 19,865,512 $0.23
Cognition Therapeutics 13,228,923 $1.55
Microbot Medical 11,859,772 $3.46
Novo Nordisk 11,633,901 $55.73
Ocugen 11,576,653 $1.20
UnitedHealth 9,734,060 $349.10
Oscar Health 9,717,213 $18.91
Moderna 9,357,304 $23.75
  • Upcoming FDA Catalysts

    • Cytokinetics (NASDAQ: CYTK) PDUFA Date

      September 26, 2025
    • Unicycive Therapeutics (NASDAQ: UNCY) PDUFA Date

      September 26, 2025
    • Jazz Pharmaceuticals (NASDAQ: JAZZ) PDUFA Date

      October 7, 2025
    • Arcutis Biotherapeutics (NASDAQ: ARQT) PDUFA Date

      October 13, 2025
    • Syndax Pharmaceuticals (NASDAQ: SNDX) PDUFA Date

      October 25, 2025
    • Merck (NYSE: MRK) PDUFA Date

      October 25, 2025

Featured Stock

C4 Therapeutics

C4 Therapeutics is pioneering a new class of small-molecule drugs that selectively destroy disease-causing proteins via degradation using the innate machinery of the cell. This targeted protein degradation approach offers advantages over traditional drugs, including the potential to treat a wider range of diseases...

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Immix Biopharma

Immix Biopharma is a clinical-stage biopharmaceutical company pioneering a novel class of CAR-T cell therapies and Tissue-Specific Therapeutics targeting oncology and immuno-dysregulated diseases with >75 patients treated to-date. The company's lead cell therapy asset is NXC-201 in multiple myeloma...

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Recursion

Recursion is a clinical stage TechBio company leading the space by decoding biology to industrialize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously expands one of the world’s largest proprietary biological and chemical datasets...

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Featured Stock

Surmodics

Viking Therapeutics is a clinical-stage biopharmaceutical company focused on the development of novel first-in-class or best-in-class therapies for the treatment of metabolic and endocrine disorders, with three compounds currently in clinical trials. Viking’s research and development activities leverage...

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