Calgary, Alberta, Canada – TheNewswire - June 24, 2025 – Voyageur Pharmaceuticals Ltd. (TSX.V:VM) (OTC Pink:VYYRF) (“Voyageur”, or the “Company”), a Canadian public company developing cost-effective imaging contrast media, is pleased to announce the signing of a Non-binding Letter of Intent ("LOI") with a Latin American based specialty distribution company to establish a strategic partnership for the distribution and commercialization of Voyageur’s radiology contrast media products.

The prospective partner is an established pharmaceutical distributor with a strong presence in Mexico and other Latin American markets where Canadian regulatory approvals are accepted. Upon final agreement, the distributor will lead marketing, sales and regulatory activities in the region. Final terms will be disclosed upon the execution of a binding distribution agreement, which is expected within 90 days.

This partnership represents a key milestone in Voyageur’s international growth strategy, further expanding the Company’s global footprint and supporting access to underserved markets with increasing demand for high-quality contrast media. “This agreement marks a significant step forward in our commercialization roadmap” said Brent Willis, CEO of Voyageur. “It reflects our continued commitment to expanding global access to our innovative, cost-effective imaging solutions. Latin America is a critical market in our expansion plan, and this partnership lays the groundwork for long term growth”

Sales of Voyageur’s barium sulfate contrast media products in Mexico and other Latin American countries will be subject to local regulatory approval processes. The distributor is expected to take the lead in preparing and submitting necessary filings with support from Voyageur’s technical and regulatory team.

About Voyageur Pharmaceuticals Ltd.

Voyageur, a Canadian public company trading under the symbol VM on the TSX Venture Exchange, is in development of barium and iodine Active Pharmaceutical Ingredients (API) that offer high-performance and cost-effective imaging contrast agents. With a strategic focus on vertically integrating the barium and iodine contrast markets, Voyageur aims to become a key player by producing its own barium and iodine. In addition, Voyageur is pursuing the development of new endo fullerene drugs.

Voyageur's business plan is set to generate cash flow by working with established third-party GMP pharmaceutical manufacturers in Canada thereby ensuring the validation of its products by regulatory agencies worldwide. As Voyageur solidifies its presence in the market, it plans to transition into a high-margin domestic manufacturer of radiology drugs

At the core of its operations, Voyageur owns a 100% interest in the Frances Creek Project. Currently, the world's pharmaceutical barium sulphate is almost entirely synthetically produced resulting in a less effective imaging quality product. Voyageur’s Frances Creek resource boasts a rare and exceptional grade mineral suitable for the pharmaceutical marketplace that Voyageur believes will replace the current synthetic products with higher quality imaging products.

Voyageur's ambitious vision is to become the first vertically integrated company in the radiology contrast media drug market. By controlling all primary input costs, from the sourcing of raw materials to final production, Voyageur believes it can ensure quality and cost efficiency. With its approach, it embodies the motto of "From the Earth to the Bottle," highlighting Voyageur's commitment to responsible sourcing and manufacturing practices.

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Neither the TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this news release.

Cautionary Statement Regarding “Forward-Looking” Information

This news release may contain certain forward-looking information and statements, including without limitation, statements pertaining to: satisfactory completion of due diligence and the entering into of the Agreement; the Company's belief that it can become one of the first to operate a fully-integrated iodine-based and barium-based pharmaceutical manufacturing platform; the Company's aim to become a key player in the barium and iodine contrast markets, the Company's plan to transition into a high-margin domestic manufacturer of radiology drugs; the Company's belief that the Frances Creek Project's mineral will replace the current synthetic products in the pharmaceutical marketplace with higher quality imaging products; and the Company's belief that it can ensure quality and cost efficiency by controlling all primary input costs. All statements included herein, other than statements of historical fact, are forward-looking information and such information involves various risks and uncertainties. There can be no assurance that such information will prove to be accurate, and actual results and future events could differ materially from those anticipated in such information. A description of assumptions used to develop such forward-looking information and a description of risk factors that may cause actual results to differ materially from forward-looking information can be found in the Company's disclosure documents on the SEDAR+ website at www.sedarplus.ca. Voyageur does not undertake to update any forward-looking information except in accordance with applicable securities laws.